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Revision Questions: Neurological (Preview)

Sample Questions

  1. Briefly describe and classify the types of epileptic seizures.
  2. What is the mechanism of action of carbamazepine?
  3. Monitoring is not required for carbamazepine. True/False
  4. What is the first line treatment for generalised, tonic-clonic seizures?
  5. What are the contraindications of sodium valproate?

Sample Answers

  1. Epileptic seizures can be classified as:
    • Partial seizures: seizures that begin at one hemisphere of the brain (localised). These are sub-classified as simple partial and complex partial seizures. Simple partial seizures have motor and sensory symptoms. Complex partial seizures have the same symptoms with the addition of impaired consciousness.
    • Generalised seizures: seizures that may involve the activity of both hemispheres of the brain and does not begin locally. These types of seizures are sub-classified into:
      • Absence seizures
      • Myoclonic
      • Clonic
      • Tonic clonic
      • Atonic
      • Infantile spasms
  2. Carbamazepine is thought to prevent neuron discharges by blocking voltage gated sodium channels.
  3. False
  4. Sodium valproate, carbamazepine
  5. Contraindications for sodium valproate include hypersensitivity, severe liver dysfunction, pancreatic dysfunction, porphyria and urea cycle disorders.

The full version has many more questions with answers included.

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